Agilent Technologies Introduces New High-Sensitivity NGS Target Enrichment Solution

New Solution Streamlines Workflow and Eliminates Sequencing Errors

SANTA CLARA, Calif.–(BUSINESS WIRE)–Agilent Technologies Inc. (NYSE: A) today introduced its newest
next-generation sequencing (NGS) library prep solution — Agilent
SureSelectXT HS — a complete target enrichment
research solution that provides total workflow management for
laboratories, from QC to target enrichment, to analysis and
interpretation.

SureSelectXT HS is a streamlined, high-sensitivity
(HS) solution for research, optimized for labs with a requirement to
sequence DNA from formalin-fixed paraffin-embedded (FFPE) samples, which
may have degraded over time. By incorporating molecular barcodes,
SureSelectXT HS improves overall precision and produces
higher complexity libraries than competing products, on a broad range of
tissue types and low- and high-quality FFPE samples.

“This customizable target enrichment technology with integrated
molecular barcode error correction enables us to detect ultra-low
mutation frequencies in very small DNA quantities,” said Dr. Marco
Gerlinger of the Institute of Cancer Research and the Royale Marsden
Hospital in London. “These features make it ideal for the detection and
tracking of clonal and subclonal variants in liquid biopsies.”

SureSelectXT HS libraries, with higher percentage reads in
targeted regions, require as little as 10 ng of starting DNA, and use
molecular barcodes to assist error correction. Additionally, faster and
more efficient processing with master-mixed reagents that require less
hands-on time, coupled with a 90-minute hybridization — the most rapid
hybridization on the market — enables labs to now move from sample to
sequencer in a single day.

“SureSelectXT HS provides robust library preparation for
low-input, degraded FFPE samples, as well as significantly reduced
turnaround time,” said Jeff Heimburger, head of genomics marketing at
Agilent. “These advances highlight Agilent’s continued commitment to
alleviating customer pain and improving lab efficiency through
innovation.”

About Agilent Technologies

Agilent Technologies Inc. (NYSE: A), is a global leader in life
sciences, diagnostics and applied chemical markets. With more than 50
years of insight and innovation, Agilent instruments, software,
services, solutions, and people provide trusted answers to its
customers’ most challenging questions. The company generated revenues of
$4.20 billion in fiscal 2016 and employs about 13,000 people worldwide.
Information about Agilent is available at www.agilent.com.

Contacts

Agilent Technologies Inc.
Naomi Goumillout, +1-781-266-2819
[email protected]